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All patients were required to have a primary regurgitant jet from malcoaptation of the middle segments of the anterior and posterior leaflets at recruitment

B Vitamins for Energy B3, B5, B6, B12 help reduce tiredness and support energy metabolism

Uraemic cardiomyopathy is characterized by extensive metabolic remodelling, including secondary carnitine deficiency, reduced fatty acid use, enhanced glucose utilization, mitochondrial dysfunction and altered expression of metabolic regulatory genes, which collectively result in impaired energetics

J Alzheimers Dis 20(s1)

Finally, due to the use of cross-sectional and casecontrol designs, we could not assess temporal associations of carnitine levels with BMD and recent osteoporotic fracture, which limited causal inference