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Sur le plan biochimique, le glutathion, sous sa forme rduite active (GSH), intervient au cur des systmes de dfense cellulaire

While the largest percentage of intracellular iron is tightly bound to or incorporated into proteins as a cofactor or for storage, small portion of intracellular iron resides in the cytosol and intracellular organelles (e.g., lysosomes) and constitutes a redox-active liable iron pool, which regulates programmed cell death including ferroptosis 42