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However, the nuclear glutathione pool resisted depletion by BSO but not with DEM

The phase I metabolism such as O- demethylenation, N- deethylation, and reduction of the -keto group, has been described in human urine, plasma, and liver microsomes, as well as in rat liver microsomes, with phase II metabolites from O- methylation and glucuronidation, and a suggested sulfation pathway 16,17,18,19

2015;25:S315

Inflammatory modulation: animal models of experimental colitis (TNBS, DSS), toxic hepatitis and joint damage documented reduction of pro-inflammatory cytokines (TNF-, IL-6, IL-1) and improvement of histological lesion scores

It can replace GLY modification and be used as a novel anti-calcification modification technology for heterogeneous tissue materials crosslinked by GLUT