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The animals were incubated with 1 l MitoSOX (final concentration 10 M) in a rocker at 20C in the dark for 24 hours

It is not approved by regulatory authorities such as the FDA for therapeutic or consumer use outside controlled research settings

After reperfusion, elevated oxidative stress and mitochondria damage lead to increased cell death across various mechanisms

Y., Xiao, Y., Qian, X

The present review features a brief introductory statement about the autophagy machinery and discusses the involvement of autophagy in seizures and epilepsies