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86, 87 In patients for whom Hunner lesions are suspected, it is appropriate to proceed to cystoscopy in order to assess for the presence of Hunner lesions (Statement 4)

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479,480 This activation often involves focal adhesion kinase (FAK), which is a critical mediator in transducing signals from integrins to promote cell cycle progression and proliferation through pathways like Ras-ERK/MAPK