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Glutamate transporters and the excitotoxic path to motor neuron degeneration in amyotrophic lateral sclerosis [in eng]

In Candida infections, host mitochondria exhibit decreased complex I and complex III activity, correlating with reduced ATP levels and impaired phagocytic killing capacity ( Moreover, gliotoxin from Aspergillus fumigatus and candidalysin from Candida albicans synergistically impair mitochondrial ATP production, weakening epithelial barrier integrity and facilitating fungal invasion ( 4.3 Fungal-induced mitochondrial ROS generation and oxidative stress One of the earliest mitochondrial responses to fungal infection is the excessive generation of mtROS

The concentration of protein-bound thiols was equal to the concentration of total thiols and disulfides minus the concentration of total small molecule thiols and disulfides, as shown in Fig

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P2X-selective purinergic antagonists are strong inhibitors of HIV-1 fusion during both cell-to-cell and cell-free infection