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Up to 10% of clinical trial participants experienced these reactions

One study found that the lowest dose of cyanocobalamin required to correct B12 deficiency in seniors is more than 200 times greater than the recommended dietary allowance (approximately 3 g daily)

CrossRef Tumor Necrosis Factor- as a Predictor for the Development of Nonalcoholic Fatty Liver Disease: A 4-Year Follow-Up Study Yun Yong Seo, Yong Kyun Cho, Ji-Cheol Bae, Mi Hae Seo, Se Eun Park, Eun-Jung Rhee, Cheol-Young Park, Ki-Won Oh, Sung-Woo Park, Won-Young Lee Endocrinology and Metabolism.2013