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(123) also found that Clostridium IV and XIVa isolated from healthy mice increased the number of systemic and lamina propria Treg cells when transplanted into germ-free mice, which in turn affected osteoclast genesis through the secretion of IL-4, IL-10, and TGF-

In the human eye, the composition and biomechanical properties (rigidity, elasticity and topology) of the ECM within the Trabecular Meshwork/Schlemms Canal (TM/SC) contribute to the regulation of intraocular pressure (IOP) and the pathogenesis of glaucoma (Keller and Peters, 2022)