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Avoid ketorolac use during the third trimester of pregnancy (starting at 30 weeks of gestation) due to the risk of premature closure of the fetal ductus arteriosus and persistent pulmonary hypertension in the neonate (2,3,5,6)

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When any large caloric deficit drives rapid weight loss, a portion of what comes off is lean mass muscle, connective tissue, organ mass, and the water they hold alongside the fat