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overexpression in a cardiotoxin muscle-injury model modulated inflammatory cytokine expression and delayed macrophage resolution, suggesting a role in the inflammatory phase of regeneration rather than a purely anabolic one

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At the metabolic level, it begins with glutamatergic activity, a process whereby increased neuronal activity results in the release of glutamate, the main excitatory neurotransmitter in the brain, into the extracellular space along the glutamate transporter EAAT3, which is exclusively located in neurons

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doi: 10.3389/fphar.2021.641210 110 BrancaJJVMorucciGBecattiMCarrinoDGhelardiniCGulisanoMet al