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Byproducts of NNMT, SAH and 1-MNA inhibit NNMT activity via a feedback mechanism (107)

These conditions include megaloblastic anemia, neurological disorders, cognitive decline, cardiovascular issues, and complications during pregnancy (Figure 2), among others

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents: To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions