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P.DentonD

In resting cells, a high ratio of AMP to ATP leads to elevated AMPK activity and diminished mTOR function

Schmit PJ, Hiyama DT, Swisher SG , Thompson JE

The induction of ferroptosis, combined with ER or AR antagonists, significantly inhibits the growth of ER-positive breast cancer or AR-positive prostate cancer, offering a new therapeutic approach for cancers with specific genetic background [48]