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Interestingly, red-blood cell zinc was borderline low in 70% of the patients in which it was measured and red-blood cell copper was slightly elevated in 35% of the patients in which it was measured

The dysfunctional TJ complexes observed in coeliac patients is thought to facilitate the entry of immunogenic gliadin into the underlying immune system, while the expression of HLA variants may also contribute to disease symptoms through attenuated immunomodulation within the intestinal lumen upon exposure to dietary components such as gliadin (Lammers et al

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Epidemiology 24 , 447453 (2013)