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ASXL1 1-645 but not ASXL1 1-591 concurrently associates with BRD4 and MLL3/4 We have previously shown that the amino acid sequence of ASXL1 (aa 607-627) serves as a binding site for the second and third PHD fingers of methyltransferases MLL3 and MLL4, denoted as MBH (MLL binding helix, ASXL1 MBH ) 10,38

Perotti A, Sessa C, Mancuso A et al (2009) Clinical and pharmacological phase I evaluation of Exherin (ADH-1), a selective anti-N-cadherin peptide in patients with N-cadherin-expressing solid tumours