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Myo-inositol oxygenase expression profile modulates pathogenic ferroptosis in the renal proximal tubule

Similarly, early administration of MMP inhibitors has shown to reduce BBB permeability and the rate of HT (251), is a potential neuroprotective therapeutic compound that may limit BBB dysfunction, preventing TJP disruption through the reduction of microglia's pro-inflammatory cytokines (252)

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It appeared to lower the intensity of H2AX signalsa marker of DNA damageand seemed to decrease apoptosis rates, as indicated by reduced Annexin-V staining

[DOI] [PMC free article] [PubMed] [Google Scholar] 154.Wilkie D.A., Latimer C.A