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Studies have shown that long-term treatment with vitamin D promotes GABA synthesis in crucial brain areas such as the prefrontal cortex, anterior cingulate cortex, and hippocampus ( While the -lactam component was intended to increase EAAT2 expression and reduce glutamate toxicity ( Additionally, studies have shown that -lactam antibiotics are associated with improved behavior and neuronal integrity

73 MorelC.FattoreL.PonsS.HayY.MartiF.LambolezB.et al (2014)

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