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This phase is critical for DNA damage repair, immune memory and homeostasis, synaptic downscaling, and clearance of debris and metabolic waste including byproducts of oxidative stress from brain tissue (Tononi and Cirelli, 2006

Overexpression of MET in cancer cells can make c-MET to be recognized as a tumor associated antigen (TAA) by CD8 cytotoxic T cells which can trigger immune system activation [71]