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The disproportionation of O 2 - (either naturally or through the action of SOD) results in the formation of H 2 O 2 , which can be fully reduced to H 2 O or partially to OH, known to be among the most potent oxidants in nature (Turrens, 2003)

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Figure 3 5.1 Mechanisms of action 5.1.1 Reduction of uremic toxins Impaired protein absorption in CKD patients causes an increase in levels of undigested or unabsorbed proteins entering the colon, creating conditions in the gut that promote the growth of proteolytic bacterial species (Bammens et al., 2003

The neuroprotective effect of EGCG on PC12 cells against CORT-induced neurotoxicity is mediated through the stimulation of the Shh signaling system

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