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Altogether, these interrelated mechanisms create a pathological environment and further progressive neuronal damage, forming the biological basis of neurodegenerative diseases

Discovery of previously unknown metabolic reactions through isotopologue similarity networking We further developed an isotopologue similarity networking approach, namely IsoNet, by combining mass spectrometry-resolved stable-isotope tracing metabolomics and isotopologue similarity networking between labeled metabolites (Fig

Vitamin E also supports skin hydration, making it look smoother and more youthful

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NF-B, on the other hand, was first identified as a transcription factor that regulates antibody release in B cells [57]