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They found that this synthetic peptide didnt cause desensitization and had a longer half-life

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Thaiss CA, Zeevi D, Levy M, Zilberman-Schapira G, Suez J, Tengeler AC, Abramson L, Katz MN, Korem T, Zmora N, Kuperman Y, Biton I, Gilad S, Harmelin A, Shapiro H, Halpern Z, Segal E, Elinav E (2014) Trans kingdom control of microbiota diurnal oscillations promotes metabolic homeostasis

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