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Because both delta sleep and GH secretion peak concurrently in the early night, DSIP's sleep-deepening effects and GH-modulating effects may represent two manifestations of the same underlying neuroendocrine circuit restoration

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doi: 10.3168/jds.2016-11018 64 JamesS

Using a larger needle to draw bacteriostatic water and solution from vials, then switching to your smaller injection needle preserves needle sharpness for more comfortable injections