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Second, probiotics have been reported to exert immunoregulatory activities, either by inducing protective cytokines, such as IL-10 and transforming growth factor-, or by suppressing pro-inflammatory cytokines, such as TNF, in the intestinal mucosa (Borruel et al

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Surface modification of proteins such as carbonic anhydrase by GSH results in significant disorder of the GSH distal to the covalent bond (Mallis et al., 2000)