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Because BPC-157 is not FDA approved for general medical use and human safety data remains limited, patients should not self-dose, order research peptides online, or use BPC-157 without medical supervision

On average, volunteers in the retatrutide clinical trial who received the study drug rather than a placebo lost an average of 70.3 pounds over about a year-and-a-half, with more than 45% of participants losing more than 30% of their body weight

Strict vegans and vegetarians are also at higher risk for deficiency since B12 occurs naturally only in animal-derived foods

For most research applications, this is the sweet spot