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Inter-individual variabilities were estimated for K a , V / F , CL/ F , and PK Base , and IIV correlations were identified between K a and V / F and between K a and CL/F (Table S1 of the Electronic Supplementary Material [ESM])

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Volume: ~0.17 mL with an insulin syringe (29-31 gauge) Timing: Once weekly, same day each week in most reported protocols IM injection community sources do not describe IM protocols, citing concern over faster absorption Reconstitution Quick Reference The following reflects dilution ratios documented in community reconstitution sources: Math: 3 mg / 2 mL = 1.5 mg/mL = 1,500 mcg/mL

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