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This epigenetic silencing effectively inhibits class-switch DNA recombination (CSR), somatic hypermutation (SHM), and plasma cell differentiation, thereby reducing the production of both T-dependent and T-independent autoantibodies (e.g., anti-dsDNA antibodies)

Peptides, which are short chains of amino acids, are crucial for many bodily functions, including hormone regulation, metabolism, and cell signaling

Potent Anti-Inflammatory: Many of the most common health care diseases have an inflammatory component as the root cause

Contrary to claudin-1, which in normal colonic epithelial cells is expressed to a minimum (even though it is highly increased in colon cancer tissue and cells 65 ), the claudin-7 protein is highly expressed in the colonic epithelium