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The following detailed exploration illuminates the intricate biological processes underpinning this complex disorder: Altered Nociceptive Processing Hyperexcitability of the dorsal horn neurons within the spinal cord leads to amplified pain signaling, even in response to non-painful stimuli (allodynia)

Depending on why it happens, its often a treatable condition

Bowatte G, Lodge CJ, Perret JL, Matheson MC, Dharmage SC

26 31 ALDH2, the primary enzyme for metabolizing acetaldehyde, is expressed strongly in the liver and adipose tissue, and more weakly in the kidneys, lungs, stomach, and skin

doi: 10.5501/wjv.v12.i2.91 113 SchulzkeJ