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Su principal desventaja frente a otros antioxidantes orales es la baja biodisponibilidad del GSH nativo , lo que ha motivado el desarrollo de formulaciones liposomales y micelares, as como el uso de precursores como la N-acetilcistena (NAC) , que aportan cistena para la sntesis endgena de glutatin

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The administration of hemin results in the boost of HO-1 expression and mitigates inflammatory responses in retinal ganglion cell injury in diabetic retinopathy, as well as diabetic wound healing, diabetic kidney function and [54,55,56]