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Furthermore, a recent large-scale comparative analysis of published mRNA microarray datasets found that PYCR1 was one of the most commonly overexpressed metabolic enzyme genes in comparison to normal tissue among the 19 represented cancer types [54]

Specific transport proteins, such as organic anion transporting polypeptides ( OTAP1B1 and OATP1B3 ), actively facilitate the transfer of bilirubin from the sinusoidal blood into hepatocytes [24]