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The detrimental effects of B12 deficiencysuch as hyperhomocysteinemia and impaired methylationare well-established and can negatively impact oocyte quality and embryo viability [19, 20], which is consistent with the lower pregnancy rates we observed at low B12 levels

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For instance, hyperesthesia occurs in 3 to 14 percent of retatrutide users and injection-site reactions span between 2 and 8 percent

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