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Data availability The datasets generated and analyzed during the current study have been made available as Supplementary Dataset S1 (metabolite levels and cognitive data)

Immune System Support: Helps maintain healthy immune function and overall wellness

Early phase (weeks 1-4) The first noticeable changes typically involve sleep quality

In parallel, the dysregulation of clock genes compromises the temporal expression of metabolic genes, completing the chain of events leading to a collapse in the temporal organization of physiological processes and triggering a progressive dysfunctional metabolic state