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YAP form a complex with TEAD [39, 42]/SLUG [42]/PDZ-binding motif (TAZ) [68]/forkhead box protein M1 (FOXM1) [53] and upregulate spindle assembly checkpoint (SAC) and ZEB1 to drive cells to enter into the senescent state, EMT conversion and apoptosis escape, while Bromodomain containing 4 (BRD4) enhances chromatin accessibility for TFs involved in both survival and dedifferentiation of DTPs via eliciting compensatory kinase genes ( K19, K14, VIM ) [108, 109]

Supplementary Table 5 (download XLSX Quantitative MS-based proteomics of proteins from HT-1080 cells treated with Fento-1

1.5 10 8 CFU/mL) (81), and used as inoculum

Wang DY, Salem JE, and Cohen JV, et al (2018) Fatal toxic effects associated with immune checkpoint inhibitors: a systematic review and meta-analysis JAMA Oncol 4 (12) 17211728 PMID: 30242316 PMCID: 6440712 31

This study aims to evaluate the effects of glutamine on metabolic variables in diabetes Mellitus and to determine possible directions for future studies