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Our analyses reveal not only the shared transcriptional targets of Ire1 and Xbp1 , but also the unique regulatory programs of these genes

Inflammatory Diseases Parkinson Disease Parkinson disease (PD) is the second most prevalent central nervous system degenerative disease, characterized by slow and progressive loss of midbrain substantia nigra dopamine with the accumulation of -synuclein in Lewy bodies and neuritis (111)

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In the presence of 100 g/mL of CME, the TNF- concentration in the culture medium was 246.8 pg/mL, which was significantly lower than that (281.0 pg/mL, 12.17% reduction) observed with unfermented matrix extract (Fig