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2.3 Assessment of metE antigen immunogenicity and efficacy using in vivo aerosol MTB challenge studies Following promising results from the MGIA experiments, we then assessed whether the metE antigen, when delivered as a DNA vaccine or as a protein/adjuvant combination, could protect against an aerosol MTB challenge in mice ( Figure 5A )

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In exploring gene-regulatory research, the peptide is thought to serve as a model for how small endogenous molecules may support tissue function at the genomic level