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Although there are data in animal models supporting that this is true, particularly in diet-induced obese mice, in which brown adipose tissue activity is regulated [8], there is no convincing evidence that this occurs in humans [6]

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Additional plateable PHHs Hum180931 (Lonza, catalog: HUCPI) were thawed and plated in hepatocyte plating medium (Lonza, catalog: MP250) overnight, then the medium was replaced with hepatocyte culture medium (Lonza, catalog: CC-3198)

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