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Gao W, Jiang L, Ge L, Chen M, Geng C, Yang G, et al

Specially, in breast cancer, oxidative stress is linked to DNA damage and mutations in key oncogenes and tumor suppressor genes, such as BRCA1 and TP53

This hypothetical adverse effect, although not clinically reported until now, is analogous to the hypothalamic-pituitary axis suppression seen with long-term use of systemic corticosteroids Exacerbation of Helicobacter pylori associated peptic ulcers: Helicobacter pylori is known to feed on macrophages and neutrophils abundant at the site of inflammation caused by the ulcer

Some people may experience mild digestive upset when they first start a supplement, but this often resolves quickly