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This activation leads to the upregulation of various cytoprotective and antioxidant proteins

In order to test a possible effect of intracellular glutathione synthesis, buthionine sulfoximine (BSO), a specific inhibitor of -glutamylcysteine synthetase, was used to block the first step of intracellular glutathione synthesis

2023 Feb 6;15(4):838

Understanding the intricate relationship between mTOR and cell death mechanisms is crucial for developing novel therapeutic strategies targeting mTOR signaling in cardiovascular diseases