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This argues against oxidative stress as the only explanation for GSH elevation in these cancers, and that elevated GSH may serve an additional function beyond ROS detoxification in lung cancer

Sharma, M

ROO is produced as an intermediate in the lipid peroxidation process through multiple chain reactions

Although, no noticeable change was observed in quercetin fed normoxia group as compared with normoxia control, but acetazolamide fed normoxic group exhibit abnormally enhanced levels of ACE 2 enzyme activity (3-fold )