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P.GrandasA.et al (2015)

More specifically, the nuclear translocation of the YAP1 protein promoted the transcription of ACSL4 and TfR1 by binding directly to their promoters with TEAD4 and reduced the GPX4 protein level post-translationally by increasing its ubiquitination

FIGURE 3 4.3.2 Lipid profile changes As shown in Figure 3, the hypothyroid group showed significant dyslipidemia that manifested as significantly elevated plasma TG, total cholesterol, and LDL-cholesterol levels, accompanied by significantly lowered plasma HDL-cholesterol levels compared to the control ones

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