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Cardiovascular:Pulmonary edema and congestive heart failure early in treatment

Diabetologia (2015) 58:1699703

Nat Rev Mol Cell Biol (2022) 23(2):93106

Tesofensine is a CNS-active triple monoamine reuptake inhibitor that suppresses appetite by prolonging serotonin, norepinephrine, and dopamine signaling in the brain