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Environment International, 34(8), 1157-1169

4.4 Clinical trials: reproductive and metabolic outcomes of MI in PCOS Across randomized trials and meta-analyses, MI consistently signals benefit for reproductive endpoints in PCOS, though the magnitude varies with phenotype, baseline IR, and treatment context (143, 148)

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Mutations of ARID1A, an epigenetic regulator, in colorectal cancer patients were found to confer resistance to cetuximab rather than bevacizumab, with a relation to the EGFR/MAPK pathway (90)