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[171] One in vitro study suggests attenuation of tamoxifen may be a concern with genistein as well

Although not entirely known, the mechanism(s) of elevation of GGT activity in patients with chronic liver disease of various etiologies may involve not only a passive release of the enzyme from the injured cells but also an accelerated release kinetics due to either increased intracellular synthesis or enhanced release into the bloodstream of GGT molecules expressed on cell surface [19]

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Following this, the same model was fitted without the interaction term and a likelihood ratio test (test = LRT) was performed to compare the full model (including all SVA factors and the interaction term) to the reduced model (including all SVA factors but not the interaction term)

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