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The calf and hamstring muscles can become weak and tight, altering gait and increasing load on the knee joint

Treatment options can include: Supplements Oral B12 : Effective for most people, even those with mild malabsorption Sublingual B12 : Dissolves under the tongue, dominantly orally with some absorption passing into the bloodsteam Injectable B12: Used in specific cases, for example if someone is not responding to oral or sublingual supplements