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RES has been shown to inhibit autophagy through the regulation of the DJ-1 protein and its impact on the MEKK1/JNK signaling pathway ( RES protects the cardiovascular system by mechanisms that include defense against ischaemic-reperfusion injury, promotion of vasorelaxation, protection and maintenance of intact endothelium, anti-atherosclerotic properties, inhibition of low-density lipoprotein oxidation, suppression of platelet aggregation and oestrogen-like actions ( 3.7 Neuroprotection Research has revealed the potential neuroprotective benefits of RES, indicating its effectiveness in mitigating the effects of aging and neurodegenerative diseases, such as Parkinsons and Alzheimers disease