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Treg and LRP1/CD91 levels before and after treatment in vitiligo patients, vs healthy individuals, show higher levels in vitiligo patients, demonstrating that abnormalities in the immune response contribute to the pathogenesis of vitiligo.22 Cytokines and chemokines Cytokines, especially IFN- and TNF-, play a crucial role in melanocyte loss and vitiligo progression

The first category includes zinc transporter families with homology to the highly affinity ZnuABC transport system of Escherichia coli

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We stress the need for biochemical tests to confirm the diagnosis and avoid wrong treatments

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