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Although L-NAME can inhibit endothelial nitric oxide synthase to cause hypertension through increased peripheral resistance (45), it seems L-NAME can cause hypertension through other alternative pathways

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note that type I is considered monoclonal cryoglobulinemia, and types II and III are classified as mixed cryoglobulinemia.[21,22] Type I Cryoglobulinemia : This disorder consists of isolated monoclonal immunoglobulin (IgM or IgG) and most commonly occurs in association with lymphoproliferative disorders

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