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Because cystine is dominant in cell culture media, xCT expression is commonly induced in most types of cells, whether lined or primary, to meet the Cys requirement and support their survival [48]

active glutathione, leads to a lack of energy which affects all cells and the nerve cells to a large extent, which can be noticed by a burn-out syndrome

Myocardial reperfusion injury

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Overall, in the presence of the terminal electron acceptor -oxygen- glycolysis is slowed down because of phosphofructokinase-1 inhibition by citrate and ATP