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World J Gastroenterol (2017) 23(28):50414

Method of using copper (II) containing compounds to accelerate wound healing

Known Side Effects Reported side effects are generally mild and infrequent: Injection site reactions: temporary redness, mild swelling, or tenderness Nausea: occasionally reported, usually mild and transient Dizziness: rare, typically with first doses Fatigue: some users report temporary tiredness Headache: infrequent, usually resolves quickly These effects typically diminish with continued use and rarely require treatment discontinuation

It has been associated with oxidative DNA damage in conditions such as aging, cancer and pro-oxidant environmental exposures

Once activated, they express -smooth muscle actin (-SMA) and synthesize collagen, as well as other extracellular matrix proteins, such as fibronectin [11]