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The accumulation of -amyloid increases oxidative stress and intracellular Ca 2+ influx, promoting neuronal toxicity in cases of Alzheimers disease ( in vitro studies on other natural compounds and computational or theoretical approaches, and should therefore be considered hypothetical, as direct in vitro or in vivo experimental data specific to bromelain are lacking

Oxidative stress is a result of an imbalance between ROS levels and antioxidative defense systems [121]

participation in the maturation of iron-sulfur clusters in proteins Build heart & brain tissue, improve immune response

Figure 4 shows three examples of the agreement between the MALDI-FTICR MSI and LCM-LC-MS/MS results

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