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Although the mechanisms that enable GPX4 expression or degradation in response to drug treatment are well understood, much more is to be learned of the complex regulatory processes that control GPX4 levels during pathological conditions

FDA drug approval is a full review process involving Phase IIII clinical trials, demonstrated safety and efficacy in humans, and post-market surveillance obligations

N., & Raghanti, M

doi: 10.1093/ajcn/79.5.727

The PCA was conducted using the FactoMineR package (52) in R, with the first five principal components capturing the primary sources of variation in the data