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Collectively, this study aims to develop and evaluate a promising radiopharmaceutical platform (camouflaged membrane-bridged radionuclide/Mn SAE), which can execute multiple action rationales and signaling pathways to dampen tumor plasticity and boost antitumor immune responses, thereby significantly elevating the therapeutic effects on tumors

Human mast cell heterogeneity: Histamine release from mast cells dispersed from skin, lung, adenoids, tonsils, and colon in response to IgE-dependent and nonimmunoiogic stimuli

However, functional roles and contribution to tumor behavior during progression and treatment response of stem cells in LGG are still being investigated, and therefore the clinical significance of stem cell marker expression in glioma progression remains unclear

As it is obvious that TRX-interaction with its target proteins occurs only transient, we do not speculate on a tight binding

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